Table 3.
The pathological and molecular characteristics of patients undergoing double surgery
| First surgery | Second surgery | |||
|---|---|---|---|---|
| No of patients | % | No of patients | % | |
| WHO grade | ||||
| II | 16 | 35.56 | 13 | 28.89 |
| III | 9 | 20.00 | 11 | 24.44 |
| IV | 20 | 44.44 | 21 | 46.67 |
| Fisher P | 0.7968 | |||
| MGMT methylation | ||||
| Unmethylated | 15 | 33.33 | 18 | 40.00 |
| Methylated | 30 | 66.67 | 27 | 60.00 |
| Fisher P | 0.6621 | |||
| Methylation level | ||||
| Very low | 5 | 16.67 | 2 | 7.41 |
| Low | 7 | 23.33 | 8 | 29.63 |
| Moderate | 15 | 50.00 | 17 | 62.96 |
| Extensive | 3 | 10.00 | 0 | 0.00 |
| Fisher P | 0.4191 | |||
| Co-deletion (1p/19q) | ||||
| No | 37 | 82.22 | 41 | 91.11 |
| Yes | 8 | 17.78 | 4 | 8.89 |
| Fisher P | 0.3529 | |||
| IDH1 (R132H, R132C) | ||||
| Normal | 26 | 57.78 | 27 | 60.00 |
| Mutated | 19 | 42.22 | 18 | 40.00 |
| Fisher P | 0.3671 | |||
| IDH2 (R172K, R172M) | ||||
| Normal | 42 | 93.34 | 43 | 95.56 |
| Mutated | 3 | 6.66 | 2 | 4.44 |
| Fisher P | 0.4944 | |||