Table 1.
Reported cases of synchronous malignant struma ovarii and thyroid carcinoma.
| Reference | Patient Age (yrs) | Ovarian Mass Size (cm) |
MSO Size (cm) |
MSO Pathology | MSO Stage | Thyroid Carcinoma Size (cm), Type |
ONCOGENIC EXPRESSION |
|---|---|---|---|---|---|---|---|
| Boyd et al [15] | 30 | 8.5x5x4 | - - - - | Papillary | No surface involvement, No LV invasion | 1.0, Papillary, NO ETE |
- - - - - - - |
|
| |||||||
| Brusca et al. [14] | 30 | 7.3x3 | 0.9 | Papillary | - - - - - - | 0.2, Papillary, No ETE |
- - - - - - - - |
|
| |||||||
| Janszen et al. [7] | 52 | 10x8 | - - - - | Follicular | - - - - - - - | 0.3, Papillary, No ETE |
- - - - - - |
|
| |||||||
| Catalina et al. [9] | 33 | 9.5x7.5x3.5 | 2.5 | Papillary | No surface involvement, No LV invasion | 1.4, Papillary With ETE, Metastatic to lymph nodes |
- - - - - |
|
| |||||||
| Leong et al. [8] | 42 | 13.5 | - - - - | Papillary | No surface involvement, No LV invasion | 0.6-0.8, Papillary, bilateral multifocal, with ETE, mets to lymph nodes |
BRAF – K-RAS – RET/PTC - |
|
| |||||||
| Marti et al. [2] | 44 | 2.4 | - - - - - | Papillary | - - - - - - - - | 0.5, Papillary with ETE, mets to lymph nodes |
BRAF - |
|
| |||||||
| Middelbeek et al [16] | 55 | 1.5 | Papillary | No surface involvement, No LV invasion | 1.2, Papillary, No ETE |
BRAF - | |
|
| |||||||
| Capitato et al. [17] | 35 | 8.2x7x6 | Papillary | No surface involvement | 1.7, Papillary, No ETE |
BRAF - | |
|
| |||||||
| Krishnamurthy et al. [18] | 51 | 13x7.6 | 0.8 | Papillary | 0.4, papillary follicular variant | - - - - | |
|
| |||||||
| Lim et al. [19] | 63 | 3x2.5x1.5 | - - - - - | Papillary | No surface involvment, No LV invasion | Papillary, mets to lymph nodes | - - - - |
|
| |||||||
| Present case | 30 | 12.9 | 6.0 | Papillary | No surface involvment, LV invasion | 0.6, Papillary, with ETE, mets to lymph nodes | BRAF – RET/PTC – TERT - |
Abbreviations: MSO, malignant struma ovarii; LV, lymphovascular; ETE, extrathyroid extension.