Figure 1.
Evaluation of CSC vaccination evoking antitumor efficacy in a mouse model. (a, b) Tumor size images on day 45 from the HO8910 tumor-bearing nude mice or on day 80 from the ID8 tumor-bearing mice after mice were initially vaccinated s.c. with 2 × 105 different inactivated vaccines three times with a 10-day interval, followed by a challenge with 1 × 106 HO8910 or 2 × 106 ID8 cells at one week after final vaccination. (c, d) Kinetic quantification of tumor sizes by measuring two perpendicular tumor diameters using calipers. (e, f) Tumor-free mice. All the data represent the mean ± SD (n = 6 per group; representative images). Statistically significant differences between the experiment group and the normal group were indicated.