Skip to main content
. 2019 Mar 17;2019:8450947. doi: 10.1155/2019/8450947

Figure 3.

Figure 3

Association between the expression of HLA-DR or ICOS on T cells and the disease activity in SLE subjects. Serum complement 3 (C3) and complement 4 (C4) were measured, and the systemic lupus erythematosus (SLE) disease activity index (SLEDAI) was evaluated for each recruited patient. Correlations between the frequency of HLA-DR+CD3+ T cells and SLEDAI (a), the frequency of ICOS+CD3+ T cells, and serum complement 3 (C3) (b) or complement 4 (C4) (c) were analyzed. Each dot represents an individual patient. Correlations were evaluated with Spearman's nonparametric test. P < 0.05 indicates a significant difference.