Table 1.
Demographics and laboratory results of diabetic foot patient cohorts.
| Patients (n) | Acute wound | Chronic wound | χ 2 or t value | P value |
|---|---|---|---|---|
| 38 | 41 | |||
| Female/male | 8/30 | 12/29 | 0.70 | 0.40# |
| Age (years) | 62.61 ± 12.31 | 65.95 ± 11.25 | -1.26 | 0.21 |
| Wagner 2 (n/%) | 15/39.47 | 9/21.95 | ||
| Wagner ≥ 3 (n/%) | 23/60.53 | 32/78.05 | 2.86 | 0.09# |
| Average hospitalization time (days) | 24.63 ± 15.81 | 34.71 ± 24.77 | -2.17 | 0.03 |
| Surgical treatment (n) | 15/39.47 | 19/46.34 | 0.38 | 0.54# |
| Debridement | 2 | 3 | ||
| Polymethylmethacrylate | 4 | 2 | ||
| Digital or ray amputation | 9 | 11 | ||
| Transtibial amputation | 0 | 3 | ||
| Vascular diseases (n/%) | 26/68.42 | 33/80.49 | 1.52 | 0.22# |
| Neuropathy (n/%) | 28/73.68 | 33/80.49 | 0.52 | 0.47# |
| Retinopathy (n/%) | 10/26.32 | 10/24.39 | 0.04 | 0.84# |
| Nephropathy (n/%) | 17/44.74 | 9/21.95 | 4.63 | 0.03# |
| Positive culture (n/%) | 30/78.95 | 31/75.61 | 0.13 | 0.72# |
| Gram-negative bacteria (n/%) | 13/34.21 | 21/51.22 | ||
| Gram-positive bacteria (n/%) | 17/54.84 | 10/24.39 | 3.81 | 0.15# |
| HbA1c < 8% (n/%) | 11/28.95 | 17/41.46 | ||
| HbA1c ≥ 8% (n/%) | 27/71.05 | 24/58.54 | 1.35 | 0.25# |
| HsCRP | 9.64 ± 5.37 | 9.29 ± 5.24 | 0.25 | 0.80 |
| PCT | 1.14±2.66 | 0.12±0.16 | 1.48 | 0.16 |
| IL-6 | 20.53 ± 17.47 | 20.35 ± 14.61 | 0.04 | 0.97 |
| White blood cells, WBC (109/L) | 8.86 ± 4.81 | 9.52 ± 5.97 | -0.54 | 0.59 |
| Neutrophil percentage (%) | 70.17 ± 15.00 | 68.70 ± 16.45 | 0.41 | 0.68 |
| Albumin (g/L) | 32.75 ± 4.49 | 32.46 ± 5.16 | 0.19 | 0.85 |
| Hemoglobin (g/L) | 115.42 ± 18.11 | 109.39 ± 19.91 | 1.41 | 0.16 |
| Ankle-brachial index, ABI | 2.56 | 0.28# | ||
| 0.9-0.99 (critical value) | 9 | 6 | ||
| 1.0-1.29 (normal range) | 26 | 34 | ||
| >1.3 (arteriosteogenesis) | 3 | 1 |
# χ 2 test. t-test was applied to all other parameters.