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. 2019 Mar 27;12:2247–2258. doi: 10.2147/OTT.S185076

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© 2019 Tang et al. This work is published and licensed by Dove Medical Press Limited

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Expression of MDM2 and EMT in samples with LAC and in adjacent tissues.

Notes: (A–C) Results of qRT-PCR analysis of E-cadherin, N-cadherin, and MDM2 (n=30). (D and E) Western blot analysis of proteins in LAC and adjacent tissues from four patients. (F) Representative images of immunohistochemistry for E-cadherin, N-cadherin, and MDM2 (200× magnification). ^*P<0.05, ^**P<0.01, and ^***P<0.001, vs adjacent tissues, respectively. GAPDH was used as reference control.

Abbreviations: Ad, adjacent tissues; Ca, cancer tissues; EMT, epithelial–mesenchymal transition; LAC, lung adenocarcinoma; MDM2, mouse double minute 2; qRT, quantitative reverse transcription.