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. 2019 Mar 24;10(3):136–148. doi: 10.5306/wjco.v10.i3.136

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Polymerase chain reaction-restriction fragment length polymorphism analysis of fibroblast growth factor receptor 4 G388 gene. Five individual tissue specimen of Head and Neck Squmous Cell Carcinoma are presented. Line 2 shows a homozygote carrier for the Glycine allele, the dominant form of the fibroblast growth factor receptor 4 (FGFR4). Lane 1, 3 and 5 show a heterozygote carrier of the FGFR4 with both alleles glycine388 and arginine388. Lane 4 shows a homozygous carrier for the arginine allele.