Crosthwaite 1985.

Methods	Design: randomised double‐blinded No. eligible: not stated No. randomised: unclear, states "100 women participated" No. analysed: 100 Drop‐outs/withdrawals: none described Years of recruitment: not stated Setting: Gynaecology Unit, Royal Melbourne Hospital
Participants	Inclusion criteria: all patients undergoing hysterectomy in hospital unit Exclusion criteria: not stated Age: mean 53 years (intervention group) vs 55 years (control group) Type of hysterectomy: abdominal or vaginal
Interventions	Treatment: 2 grams tinidazole (antiprotozoal): Control: placebo Route: oral Single/multiple doses: single Timing of doses: 12 hours preop
Outcomes	Postoperative infection, early Abdominal wound infection Urinary tract infection Pelvic infection Other serious infection Adverse effects (narrative data only)
Funding	Pfizer
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Described as randomised; method not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Described as "double‐blind"; method not described
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not categorically stated how many women were randomised
Selective reporting (reporting bias)	Unclear risk	Insufficient information in the methods section to detect presence of selective reporting
Other bias	Low risk	Baseline demographic characteristics similar between treatment groups