Schepers 1981.

Methods	Design: randomised double‐blinded (abstract only) No. eligible: not stated No. randomised: 107 No. analysed: 103 Drop‐outs/withdrawals: 4 (reasons not reported) Years of recruitment: not stated Setting: The Netherlands
Participants	Inclusion criteria: premenopausal women undergoing abdominal hysterectomy Exclusion criteria: not stated Age: not stated Type of hysterectomy: abdominal
Interventions	Treatment: deposition (second‐generation cephalosporin) Control: placebo Route: IV Single/multiple doses: multiple Timing of doses: first dose 30 minutes preoperatively, second dose 6 hours later
Outcomes	Postoperative infection Adverse effects (narrative data only) Follow‐up: not stated
Funding	Not stated
Notes	No extractable data ‐ no denominators
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Described as randomised; no additional details
Allocation concealment (selection bias)	Unclear risk	Method not described
Blinding (performance bias and detection bias) All outcomes	Unclear risk	States "double‐blind"; no additional details
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Proportions of withdrawals and reasons for withdrawal/drop‐out not reported
Selective reporting (reporting bias)	High risk	Data not available on all prespecified outcomes; thus evidence of selective reporting
Other bias	Unclear risk	Insufficient detail to determine risk