Skip to main content
. Author manuscript; available in PMC: 2019 Sep 17.
Published in final edited form as: Chem Soc Rev. 2018 Sep 17;47(18):7027–7044. doi: 10.1039/c8cs00278a

Fig. 5.

Fig. 5

Investigating aggregate composition and configuration using FRET. (a) Schematic depiction of a supramolecular system in which FRET allowed discrimination between the co-assembly and self-sorting of two stereoisomers (green and purple). Image based on ref77. (b) By judiciously functionalizing DNA structures with a FRET pair (blue and yellow), it becomes possible to distinguish between correctly and misassembled analogues. Image based on ref78. (c) Three different DNA based structures labeled with fluorophores (stars), allowing FRET to take place from the outside to the inside of the structure. (d) The photoluminescence intensity of the dendrimer construct with two, three and four fluorophores in the FRET cascade (black arrows depicted FRET). The FRET efficiency for each added step in the cascade is depicted as well and allows for discrimination between the three types of structures. Image c and d adapted with permission from ref79. Copyright 2017, American Chemical Society.