Table 2.
Univariate and multinomial analysis to determine characteristics associated with trajectory group membership
| Characteristic | Group 1 (n = 38) | Group 2 (n = 48) | Group 3 (n = 131) | Group 4 (n = 43) | Univariate P Value | Multinomial P Value |
|---|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | n (%) | |||
| Female sex | 23 (61) | 12 (25) | 72 (55) | 30 (70) | <0.001 | 0.001 |
| Non-Hispanic white | 35 (92) | 36 (75) | 97 (74) | 32 (74) | 0.122 | — |
| Prehospital dialysis | 2 (5) | 4 (8) | 11 (8) | 3 (7) | 0.970 | — |
| Home NIPPV | 4 (11) | 2 (4) | 13 (10) | 1 (2) | 0.269 | — |
| Received standardized rehabilitation therapy | 14 (37) | 21 (44) | 70 (53) | 24 (56) | 0.207 | 0.428 |
| Home oxygen | 11 (29) | 12 (25) | 30 (23) | 2 (5) | 0.028 | 0.467 |
| |
Mean (SD) |
Mean (SD) |
Mean (SD) |
Mean (SD) |
|
|
| Age | 63.3 (11.6) | 65.0 (12.4) | 56.0 (13.7) | 42.4 (15.3) | <0.001 | <0.001 |
| PaO2:FiO2* | 175.3 (81.0) | 172.7 (93.6) | 188.4 (82.8) | 183.9 (81.4) | 0.370 | — |
| APACHE III* | 78.8 (23.8) | 79.4 (22.4) | 69.8 (24.6) | 69.4 (30.8) | 0.015 | 0.092 |
| Hospital LOS (d) | 21.5 (19.1) | 16.1 (23.4) | 11.7 (8.4) | 8.8 (5.1) | <0.001 | — |
| ICU LOS (d) | 11.2 (11.1) | 6.8 (5.9) | 6.1 (5.4) | 4.9 (3.4) | 0.004 | 0.003 |
| Ventilator days | 9.5 (12.2) | 5.4 (5.7) | 4.8 (5.9) | 3.8 (3.0) | 0.066 | — |
| Restraint days | 5.6 (8.9) | 3.0 (5.2) | 2.2 (3.4) | 2.0 (2.6) | 0.145 | 0.422 |
| Continuous IV sedation days | 4.3 (5.3) | 2.2 (2.8) | 3.0 (4.1) | 3.0 (2.6) | 0.086 | 0.004 |
Definition of abbreviations: APACHE = Acute Physiology and Chronic Health Evaluation; FiO2 = fraction of inspired oxygen; LOS = length of stay; ICU = intensive care unit; IV = intravenous; NIPPV = noninvasive positive pressure ventilation; PaO2 = arterial oxygen tension pressure; SD = standard deviation.
*
Measured at enrollment.