Fig. 4. Treatment algorithm for palliative systemic therapy.
HER2 = human epidermal growth factor receptor 2; XP = capecitabine and cisplatin; FP = fluorouracil and cisplatin; IHC = immunohistochemistry.
*HER2 IHC 3+ or IHC 2+ and in situ hybridization-positive; †Evaluation of patient performance status, comorbidities, and organ function.