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. 2019 Mar 27;5(3):e01373. doi: 10.1016/j.heliyon.2019.e01373

Fig. 9.

Fig. 9

The Effect of FAESP on Pancreas histopathology (H&E, Hematoxylin-Eosin Stain). (A) The typical architecture with normal Islets of Langerhans with granulated cytoplasm and acini tissues in control rats, (B) Normal Islets of Langerhans with granulated cytoplasm and acini tissues were healthy in control-treated rats, (C) Irregular necrotic pancreatic acini and cytoplasmic degeneration, insulitis with lymphocytic infiltrations, atrophy, destruction of β cells and irregular outlining of the Islets of Langerhans markedly seen in STZ-induced diabetic control rats, (D) FAESP resulted in gradual increase in the restoration in the acinar cells and Islets of Langerhans by the recovery of the damaged islets and an improvement in some beta cells, (E) Glibenclamide resulted in restoration in the exocrine acinar cells, Islets of Langerhans and increased cellularity of β-cell in pancreatic cells. IL: Islets of Langerhans, AC: Acinar cells, NC: Necrotic Change, EX: Exocrine, C: Congestion.