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. 2019 Feb 5;41:214–224. doi: 10.1016/j.ebiom.2019.01.052

Fig. 1.

Fig. 1

V-ATPase pump conformation distinguishes aggressive gliomas from indolent LGG a) Expression (RNAseq data) of genes encoding all V-ATPase pump subunits (n = 20) in primary low-grade/IDH-mutated gliomas (LGG/IDHmut; n = 330) and glioblastoma (GBM; n = 75) from the TCGA dataset (training set). b) Cartoon showing V-ATPase pump conformation in LGG/IDHmut or GBM based on gene expression data determined in a.V0B encodes for subunit c”.