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. 2019 Feb 22;13(4):928–945. doi: 10.1002/1878-0261.12449

Figure 2.

Figure 2

Downregulation of TARBP2 enhances SR in HCC cells. (A–H) Effect of TARBP2 expression on SR in HCC cells. TARBP2 was overexpressed in Huh7/SR cells (A) and PLC5/SR cells (C) for 48 h. TARBP2 was knocked down in Huh7 (E) and PLC5 (G) cells. TARBP2 protein expression was determined via western blot analysis. Cell viability was measured using the MTT assay (B, D, F, and H). (I, J) Effect of TARBP2 ΔC4 expression on SR in Huh7/SR cells. TARBP2 and truncated C4 TARBP2 protein expression was determined via western blot analysis (I). Cell viability was measured via the MTT assay (J). Data are presented as mean ± SEM, with at least n = 3 per group. Multigroup comparisons were analyzed by two‐way ANOVA with Tukey's post hoc test. P values < 0.05 were considered statistically significant. *P < 0.05; **P < 0.01; or ***P < 0.005.