Table 1.
Subject characteristics
| Young (n = 10) | Middle Aged (n = 10) | Old (n = 16) | |
|---|---|---|---|
| Age (years) | 27 ± 2 | 54 ± 2* | 75 ± 2* , # |
| Male (male/total n) | 6/10 | 5/10 | 10/16 |
| Female (female/total n) | 4/10 | 5/10 | 6/16 |
| Height (cm) | 180 ± 9 | 179 ± 9 | 175 ± 13 |
| Body mass (kg) | 70.5 ± 12 | 73 ± 11 | 77.1 ± 13 |
| Body mass index (kg m−2) | 20.6 ± 6 | 21 ± 5 | 24.5 ± 5 |
| Systolic blood pressure (mmHg) | 120 ± 6 | 122 ± 4 | 129 ± 9 |
| Diastolic blood pressure (mmHg) | 79 ± 5 | 76 ± 5 | 80 ± 8 |
| Glucose (mg dL−1) | 109 ± 5.1 | 109.9 ± 5.7 | 108 ± 7.6 |
| Blood urea nitrogen (mg dL−1) | 18 ± 3.0 | 19.3 ± 3.0 | 20.5 ± 4.0 |
| Creatinine (mg dL−1) | 1 ± 0.3 | 0.9 ± 0.4 | 1.2 ± 0.5 |
| Albumin (g dL−1) | 4.0 ± 0.3 | 4.0 ± 0.3 | 4.1 ± 0.5 |
| Lactate dehydrogenase (U L−1) | 497.4 ± 42.8 | 502.6 ± 30.1 | 505 ± 40.1 |
| Hemoglobin (g dL−1) | 15.6 ± 0.5 | 15.1 ± 0.9 | 14.1 ± 0.5 |
| White blood cells (thousands per microlitre, K μL−1) | 4.0 ± 1.0 | 4.9 ± 2.0 | 7.3 ± 0.9 |
| Red blood Cells (millions per microlitre, M μL−1) | 5.2 ± 0.9 | 4.7 ± 0.6 | 4.6 ± 0.9 |
| Lymphocytes (%) | 36.3 ± 5.0 | 31.5 ± 3.5 | 28 ± 7.4 |
| Monocytes (%) | 8.5 ± 1.0 | 8.5 ± 1.8 | 8 ± 3.3 |
| Medications (users/n) | |||
| Diuretics | 0/10 | 0/10 | 1/16 |
| Angiotensin‐ converting enzyme inhibitors | 0/10 | 0/10 | 1/16 |
| Diabetic drugs | 0/10 | 0/10 | 1/16 |
| Statins | 0/10 | 0/10 | 0/16 |
Data are expressed as the mean ± SE or number of subjects (of the total number; n). *Significantly different from Young subjects, P < 0.05. ≠Significantly different from Middle Aged subjects, P < 0.05