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. 2019 Jan 19;13(4):757–780. doi: 10.1002/1878-0261.12425

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© 2018 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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FZD7‐TWIST1 signature predicts poor survival. (A) Scatter plot showing the correlation between FZD7 (y‐axis) and TWIST1 (x‐axis) mRNA expression in a Japanese OC cohort (GSE30311). (B) Distribution of FZD7‐TWIST1 signature score (y‐axis) among the Epi‐A (dark green), Epi‐B (light green), Mes (red), Stem‐A (blue), and Stem‐B (purple) subtypes in CSIOVDB. Kaplan–Meier curves of median overall survival (C), disease‐free survival (E), and the highest and lowest quartiles of the FZD7‐TWIST1 signature score for overall survival (D), disease‐free survivals (F) in OC patients. Stratified by the first and last quartiles of the FZD7‐TWIST1 signature score.