Fig. 1.

FA2H expression is significantly reduced in gastric cancer tissues.

a) Western blotting for Gli1 and FA2H proteins in gastric cancer tumors. Eighteen randomly selected pairs of gastric cancer tumors (T) and matched surrounding normal tissues (N) are presented.

b) IHC staining of Gli1 and FA2H in representative carcinoma and the surrounding tissue of gastric cancer (scale bar, 100 μm).

c) Column scatter plots showing the difference of Gli1 and FA2H expression between 117 human gastric cancer tumors and matched surrounding normal tissues. Statistical significance are indicated with asterisks, where ***, P < 0·001.

d) Scatter plot diagram showing a trend of the negative relationship between Gli1 and FA2H expression levels in 117 gastric cancer tissue samples.