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MyD88 signaling is not responsible for oxLDL-induced DPP4 up-regulation.
Bone marrows isolated from wild-type (WT) or Myd88−/− mice were used for the induction of BMMs. The expressions of DPP4 on both WT and Myd88−/− BMMs were detected by imaging flow cytometry after 24-h treatment of 25 μg/mL oxLDL. Representative images (A), histograms (B) and statistical analysis of DPP4+ macrophage frequency (C) or DPP4 MFI (D) are shown. *, p < .05 compared to UT controls.
