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. 2019 Feb 13;41:584–596. doi: 10.1016/j.ebiom.2019.02.001

Fig. 5.

Fig. 5

Gene expression signatures of T cells and keratinocytes in cGVHD and aGVHD humanised mice.

(a) Venn diagrams indicating differentially expressed genes in splenic T cells among cGVHD and aGVHD humanised mice. (b) Differentially expressed genes among skin and spleen T cells in acute and chronic GVHD mice and non-Tg NSG humanised mice. (c) KEGG pathway enrichment analysis and (d) transcription factor (TF) enrichment analysis of skin T cells. (e) Venn diagrams indicating differentially expressed genes in skin keratinocytes from cGVHD and aGVHD humanised mice. (f) Dimensionality reduction plot using tSNE. (g) KEGG pathway enrichment analysis and (h) transcription factor (TF) enrichment analysis of skin keratinocytes.