Table 1.
CHO cell lines used in this study
| Cells | Parent cells | Phenotype | Reference |
|---|---|---|---|
| 3B2A | CHO-K1 | Wildtype expressing human CD59 and DAF | 33 |
| PIGS KO | 3B2A | PIGS-deficient | This study |
| 3BT5 | 3B2A | SLC35A2-deficient (Lec8 phenotype) | 14 |
| 3BT5-PIGS KO | 3BT5 | SLC35A2 and PIGS-deficient | This study |
| C19 | 3B2A-FF8 | PGAP5-deficient | 19 |
| C19-PIGS KO | C19 | PGAP5 and PIGS-deficient | This study |
| C19-PIGS-SLC35A2 DKO | C19-PIGS KO | PGAP5, PIGS, and SLC35A2-deficient | This study |
| C10 | 3B2A | PGAP1-deficient | 18 |
| C10-PIGS KO | C10 | PGAP1 and PIGS-deficient | This study |
| C10-PIGS-SLC35A2 DKO | C10-PIGS KO | PGAP1, PIGS, and SLC35A2-deficient | This study |
| 3BT5-PGAP3 KO | 3BT5 | PGAP3 & SLC35A2-deficient | 14 |
| 3BT5-PGAP3-PIGS DKO | 3BT5-PGAP3 KO | PGAP3, SLC35A2, and PIGS-deficient | This study |
| 3BT5-PIGS-PGAP2 DKO | 3BT5-PIGS KO | PGAP2, SLC35A2, and PIGS-deficient | This study |
| 3BT5-PIGZ KO | 3BT5 | PIGZ and SLC35A2-deficient | This study |