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. 2019 Mar 21;30(4):664–677. doi: 10.1681/ASN.2018080814

Table 5.

Comparison of mean scores and validity statistics by self-evaluated severity of kidney disease symptomsa

Measure Mean (SD) Score F Statistic η2b RV (95% CI)
Not Notable, n=148 Mild, n=120 Moderate, n=131 Severe, n=50
KDQOL-36
 Burden (+) 81.6 (22.9) 63.8 (23.1) 48.0 (25.7) 31.6 (25.2) 74.5c 0.33 1.0
 Effects (+) 86.9 (13.2) 75.9 (17.4) 61.6 (21.6) 52.8 (23.7) 66.2c 0.31 0.89 (0.65 to 1.21)
 Symptoms (+) 86.1 (10.8) 79.4 (12.5) 68.0 (16.0) 62.5 (18.3) 58.6c 0.28 0.79 (0.53 to 1.16)
CKD-QOL
 CKD-QOL-6 (−) 40.0 (5.3) 45.6 (6.4) 52.9 (7.7) 56.5 (8.4) 123.0c 0.45 1.65 (1.24 to 2.21)d
 CKD-QOL-CAT (−) 37.8 (7.2) 45.9 (7.3) 53.0 (7.7) 56.3 (6.3) 136.2c 0.48 1.83 (1.36 to 2.45)d
 Three- or six-item CAT (−) 38.6 (6.2) 45.9 (7.5) 53.2 (8.0) 56.5 (6.5) 131.7c 0.47 1.77 1.29 to 2.39)d
SF-12v2
 PCS (+) 46.6 (9.7) 42.6 (9.8) 35.1 (9.9) 32.5 (9.7) 45.1c 0.23 0.61 (0.37 to 0.95)d
 MCS (+) 53.8 (9.1) 50.7 (10.1) 47.6 (9.8) 46.1 (11.8) 12.6c 0.08 0.17 (0.07 to 0.31)d

Means are unadjusted. 95% CI, 95% confidence interval.

a

Self-reported response to “How would you rate the severity of your kidney disease symptoms in the past 4 weeks?”: not noticeable, mild, moderate, severe/very severe.

b

η2 estimate of variance explained by groups (see text); significance is same as F ratio.

c

P<0.001 (see text).

d

P<0.05 (see text).