Table 2.

Description of the histologic findings

Histologic Lesions	AMVR without anti-HLA DSAs, n=38	AMVR with anti-HLA DSAs, n=20	P Value
Glomerulitis (g)
% With a g score >0	38 (100.0%)	18 (90.0%)	0.11
g score, mean±SD.	2.1±0.8	1.7±0.9	0.18
Peritubular capillaritis (ptc)
% With a ptc score >0	36 (94.7%)	19 (95.0)	1.0
ptc score, mean±SD	2.0±0.9	1.7±0.7	0.66
C4d deposition, C4d
% With a C4d score >0	9 (23.7%)	3 (15.0%)	0.52
C4d score, mean±SD	0.5±1.1	0.5±0.8	0.98
Interstitial infiltrates (i)
% With an i score>0	21 (55.3%)	2 (10.0%)	<0.001
i score, mean±SD.	0.9±1.0	0.1±0.3	0.003
Tubulitis (t)
% With a t score >0	14 (36.8%)	14 (70.0%)	0.03
t score, mean±SD	1.1±1.1	0.5±0.7	0.02
TCMR diagnostic criteria, n (%)	8 (21.1)	2 (10.0)	0.18
IA	3 (8.8)	2 (10.0)	0.29
IB	3 (8.8)	0 (0)	0.27
IIA	0 (0)	0 (0)	1.00
IIB	1 (2.6)	0 (0)	1.00
III	1 (2.6)	0 (0)	1.00
Vasculitis (v)
% With a v score >0	23 (60.5%)	3 (15.0%)	<0.001
v score, mean±SD	1.3±1.1	0.3±0.8	<0.001
Interstitial hemorrhages, n (%)	12 (31.6)	3 (15.0)	0.22
Thrombotic microangiopathy, n (%)	6 (15.8)	0 (0.0)	0.08
Allograft glomerulopathy (cg)
% With a cg score >0	0 (0.0%)	0 (0.0%)	1.00
cg score, mean±SD	0.0±0.0	0.0±0.0	1.00
Mesangial expansion (mm)
% With an mm score >0	2 (5.3%)	0 (0.0%)	0.54
mm score, mean±SD	0.1±0.4	0.0±0.0	0.59
Interstitial fibrosis (ci)
% With a ci score >0	4 (10.5%)	4 (20.0%)	0.43
ci score, mean±SD	0.2±0.7	0.3±0.6	0.97
Tubular atrophy (ct)
% With a ct score >0	4 (10.5%)	4 (20.0%)	0.42
Ct score, mean±SD	0.2±0.7	0.2±0.4	0.80
Chronic vascular changes (cv)
% With a cv score >0	16 (42.1%)	13 (65.0%)	0.16
cv score, mean±SD	1.0±1.1	0.9±1.1	0.87
Arteriolar hyalinosis (ah)
% With an ah score >0	15 (39.5%)	11 (55.5%)	0.28
ah score, mean±SD	0.8±0.9	0.8±1.1	0.59

TCMR, T cell mediated rejection.