Fig. 3.

Experimental chronic kidney disease (CKD) induced significant renal microvascular rarefaction and remodeling in both kidneys. A and B: representative pictures of renal microvascular (MV) density (3-dimensional μCT reconstruction) and quantification (MV density of microvessels of diameter between 0 and 200, 200 and 300, and 300 and 500 μm. C: quantification of MV media to lumen ratio (both kidneys). D: representative protein expression (3 bands/group) of VEGF and Flk-1 receptor in normal pigs and pigs after 14 wk of CKD. *P < 0.05 vs. normal.