Table 3.

Body weight, degree of stenosis, MAP, plasma cholesterol (total), plasma creatinine, BUN, albuminuria (spotted urine), and renal volume in normal animals and animals with CKD

Parameter	Normal	CKD
Body weight, kg	59.2 ± 8.8	68.8 ± 2.9
Degree of stenosis, %	0.0 ± 0.0	71.8 ± 10.2*
MAP, mm/Hg	92.4 ± 4.6	156.4 ± 8.7*
Cholesterol, mg/dl	74.9 ± 5.6	831.9 ± 34.3*
Plasma creatinine, μmol/l	112.3 ± 5.8	203.2 ± 13.2*
BUN, mg/dl	4.8 ± 0.4	6.6 ± 0.6*
Albuminuria, mg/dl	1.68 ± 0.04	2.45 ± 0.3*
Renal volume, ml	198.1 ± 13.3	132.6 ± 12.8*

Values are means ± SE; n = 7/group. BUN, blood urea nitrogen; CKD, chronic kidney disease; MAP, mean arterial pressure. Parameters were obtained after 14 wk of observation.

^*P < 0.05 vs. normal.