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. 2019 Mar 9;5(1):10–25. doi: 10.1089/aivt.2018.0020

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© Troy D. Hubbard et al. 2019; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 6. — Relative activity of botanical/dietary extracts to the Tox21 10k library. Chemical library data were restricted to 6745 chemicals. The most active test lot within each botanical group is labeled. Cumulative distribution plot of botanical/dietary extract and Tox21 library biological activity rank based on (A) number of assays in which the test substance was active and (B) sum of the scaled wAUC across all assays. Cumulative line plots indicate fraction of Tox21 (gray line) and botanical/dietary extracts (blue line) that correspond to cumulative activity based on (C) number of actives and (D) sum of scaled wAUC data.