Table 2.
Indicators of the severity of SARI by pathogen and age
| SARI cases | RSV | Adenovirus | Influenza | Multiple Viruses | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No (%) | OR (95% CI) |
P* | No (%) | OR (95% CI) | P$ | No (%) | OR (95% CI) | P$ | No (%) | OR (95% CI) | P$ | No (%) | OR (95% CI) | P$ | |
| All participants | |||||||||||||||
| Ventilation | 100/ 1,075 (9) |
1.280 (0.703- 2.329 |
0.419 | 43/485 (9) |
0.177 (−1.005- 0.185) |
0.866 | 7/105 (7) |
1.293 (0.682- 2.452) |
0.431 | 17/77 (22) |
3.123 (1.743- 5.598) |
0.000 | 13/174 (7) |
0.755 (0.412- 1.386) |
0.365 |
| ICU | 219/ 1,075 (20) |
0.972 (0.706- 1.337) |
0.861 | 82/485 (17) |
1.897 (12.591- 13.635) |
0.017 | 22/105 (21) |
1.040 (0.634- 1.707) |
0.876 | 36/77 (47) |
3.910 (2.431- 6.290) |
0.000 | 41/174 (23) |
0.225 (0.162- 0.612) |
0.254 |
| Death | 24/ 1,075 (2) |
0.00 (0.941- 0.966) |
0.557 | 12/485 (2) |
0.530 (−1.215- 0.625) |
0.637 | 2/105 (2) |
0.837 (0.194- 3.609) |
0.811 | 4/77 (5) |
0.986 (−0.114- 2.085) |
0.079 | 4/174 (2) |
0.036 (1.050- 1.122) |
0.948 |
| Severe Outcome | 219/ 1,075 (20) |
0.972 (0.706- 1.337) |
0.861 | 82/485 (17) |
1.433 (4.698- 6.132) |
0.021 | 22/105 (21) |
1.047 (0.638- 1.738) |
0.857 | 36/77 (47) |
3.937 (2.447- 6.334) |
0.000 | 41/174 (23) |
0.232 (0.155- 0.619) |
0.240 |
| Children <18 years | |||||||||||||||
| Ventilation | 66/ 981 (7) |
1.032 (0.305- 3.541) |
0.952 | 36/485 (8) |
0.894 (0.566- 1.413) |
0.632 | 7/105 (7) |
0.907 (04.05- 2.032) |
0.812 | 5/77 (6) |
1.785 (0.676- 4.713) |
.0243 | 13/174 (7) |
0.995 (0.536- 1.849) |
0.988 |
| ICU | 178/ 981 (18) |
0.983 (0.503- 1.924) |
0.961 | 68/485 (14) |
0.838 (0.594- 1.182) |
0.314 | 11/105 (10) |
0.691 (0359- 1.330) |
0.268 | 10/77 (13) |
2.008 (0.952- (4.237) |
0.067 | 32/174 (18) |
1.418 (0.921- 2.185) |
0.113 |
| Death | 13/ 981 (1) |
0.973 (0.960- (0.987) |
0.784 | 12/485 (2) |
1.363 (0.583- 1.385) |
0.474 | 2/105 (2) |
0.966 (0.222- 4.198) |
0.963 | 2/77 (2) |
2.640 (0.594- 11.740) |
0.202 | 4/174 (2) |
1.162 (0.338- 3.479) |
0.789 |
| Severe Outcome | 178/ 981 (18) |
0.983 (0.503- 1.924) |
0.961 | 68/485 (14) |
0.849 (0.602- 1.199) |
0.353 | 11/105 (10) |
0.697 (0.362- 1.342) |
0279 | 10/77 (13) |
2.024 (0.959- 4.271) |
0.064 | 32/174 (18) |
1.432 (0929- 2.206) |
0.114 |
| Adults >18 years | |||||||||||||||
| Ventilation | 34/94 (36) |
1.357 (0.645- 2.856) |
0.421 | 7/485 (1) |
0.966 (0.114- 2.085) |
0.078 | 0/105 (0) |
2.991 (0.851- 10.514) |
0.088 | 12/77 (16) |
2.878 (1014- 8.166) |
0.052 | 0/174 (0) |
0.787 (0.669- 0.885) |
0.063 |
| ICU | 41/94 (44) |
1.100 (0.704- 1.718) |
0.675 | 14/485 (3) |
1.493 (0.282- 2.452) |
0.527 | 11/105 (10) |
3.235 (0.671- 15.593) |
0.143 | 26/77 (34) |
0.929 (0.392- 2.198) |
0.866 | 9/174 (5) |
0.606 (0.203- 1.815) |
0.371 |
| Death | 11/94 (12) |
0.934 (0.912- 0.965) |
0.793 | 0/485 (0) |
0.848 (0.437- 1.196) |
0.691 | 11/105 (10) |
0.859 (0.790- 0.933) |
0.645 | 2/77 (2) |
0.413 (0.324- 0.527) |
0.351 | 0 (0) | 0.826 (0.752- 0.907) |
0.763 |
| Severe Outcome | 41/94 (44) |
1.100 (0.704- 1.718) |
0.675 | 14/485 (3) |
1.493 (0.282- 2.452) |
0.527 | 0/105 (0) |
3.235 (0.671- 15.593) |
0.143 | 26/77 (34) |
0.929 (0.392- 2.198) |
0.866 | 9/174 (5) |
0.606 (0.203- 1.815) |
0.371 |
*P for comparison between virus-infected (SARI-positive) and non-infected (SARI-negative) individuals. P$ for SARI patients with a positive result for that pathogen compared to a reference group of tested SARI patients with a negative result for that pathogen. RSV Respiratory syncytial virus, PIV Para-influenza virus, ICU Intensive care unit, Severe outcome is defined as illness requiring ventilation or ICU or resulting in death