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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Leuk Res. 2019 Jan 7;77:42–50. doi: 10.1016/j.leukres.2018.11.010

Table 3.

Correlation of cytogenetic aberrations with patient-specific response to JQ1.

BET Inhibitor (JQ1) - Patients with Chromosome aberrations
Patient ID Drugs Tested Clinical Response Simulation Response Correlation Status 7q-del / Monosomy 7 Trisomy 8 5q-del 19p-amp 22q-del
1953 JQ1 Responder Responder MATCH Y Y Y
2236 JQ1 Responder Responder MATCH Y
2500 JQ1 Responder Responder MATCH Y
2612 JQ1 Responder Responder MATCH Y
4006 JQ1 Non-Responder Non-Responder MATCH Y Y Y
2633 JQ1 Responder Responder MATCH Y Y
2079 JQ1 Responder Responder MATCH Y
2443 JQ1 Responder Responder MATCH Y
1924 JQ1 Responder Responder MATCH Y
1727 JQ1 Responder Responder MATCH Y
2704 JQ1 Responder Responder MATCH Y
4324 JQ1 Responder Responder MATCH Y
2690 JQ1 Responder Responder MATCH Y
4043 JQ1 Responder Responder MATCH Y
2452 JQ1 Responder Responder MATCH Y
2315 JQ1 Responder Responder MATCH Y
2426 JQ1 Responder Responder MATCH Y
2333 JQ1 Responder Responder MATCH Y