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. 2019 Mar 18;2019:9864841. doi: 10.1155/2019/9864841

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Copyright © 2019 Yun-fei Xie et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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UPLC-LTQ/Orbitrap MS TIC chromatograms of the plasma samples from six groups in positive and negative modes. 1. Uridine 5'-monophosphate (UMP); 2. Spermidine; 3. L-Lysine; 4. Carnitine; 5. L-Arginine; 6. L-Tyrosine; 7. N-Formylanthranilic acid; 8. L-Phenylalanine; 9. Leucine; 10. L-Tryptophan; 11. L-Isoleucine; 12. Vanillylmandelic acid; 13. Catechol; 14. Linoleate; 15. Citric acid; 16. Adenosine; 17. Deoxycholic acid. Healthy control group (A). AIA model group (B). Therapy group (C1). Efficacy enhancing combination group (C2). Toxicity group (D1). Toxicity reducing combination group (D2).