Table 2.
Effect of metformin on oxidative stress in patients with acute cerebral stroke and type 2 diabetes (n=40).
| Group | MDA (μmol/L) | SOD (U/L) | GSH-PX (U/L) | |||
|---|---|---|---|---|---|---|
| Before treatment | After treatment | Before treatment | After treatment | Before treatment | After treatment | |
| Metformin combination treatment group | 4.95±0.96 | 2.23±0.74ab | 27.46±9.18 | 36.72±9.92ab | 155.4±24.7 | 188.2±20.1ab |
| Insulin group | 4.97±0.87 | 3.29±0.83a | 27.32±8.92 | 31.81±8.97a | 153.6±26.8 | 164.3±27.8a |
| t value | 1.122 | 5.721 | 0.542 | 7.246 | 0.361 | 7.324 |
| P value | 0.286 | <0.001 | 0.637 | <0.001 | 0. 794 | <0.001 |
a
Compared with before treatment, P<0.05, the difference was statistically significant;
b
compared with the control group, P<0.05, the difference was statistically significant.