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FOXP2 is a direct target of miR-222-3p. (A, B) Luciferase assay revealed that miR-222-3p directly binds to the 3′UTR region of FOXP2. (C) Western blot analysis of FXOP2, caspase-3, cleaved caspase-3, PARP, cleaved PARP, Bax, and P-gp proteins in LoVo/S cells, LoVo/ADR cells, and LoVo/ADR + miR-222-3p inhibitor cells. FOXP2 – forkhead box protein P2.
