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. 2019 Apr 1;2019(4):CD004149. doi: 10.1002/14651858.CD004149.pub3

2.4. Analysis.

Comparison 2 CIMT versus a high‐dose comparison, Outcome 4 Data table.

Data table
Study Assessment period CIMT(mean) SD N High dose (mean) SD N Mean difference[95% CI]
Quality of Upper Extremity Skills Test (QUEST) ‐ Dissociated Movement
Hoare 2013 Baseline to immediately following intervention (change) 3.6 19.05 17 3.11 13.87 17 0.49 [‐10.71, 11.69]
Hoare 2013 Baseline to 2 weeks to 4 months post‐intervention (change) ‐2.43 17.51 17 3.78 9.88 17 ‐6.21 [‐15.77, 3.35]
Hoare 2013                
QUEST ‐ Grasps
Hoare 2013 Baseline to immediately following intervention (change) 3.11 19.81 17 3.31 14.39 17 ‐0.20 [‐11.84, 11.44]
Hoare 2013 Baseline to 2 weeks to 4 months post‐intervention (change) 8.58 8.84 17 0.62 18.05 17 7.96 [‐1.59, 17.51]
Hoare 2013                
Melbourne Assessment
Sakzewski 2015a Baseline to immediately following intervention (change) ‐1.1 5.5 24 1.2 5.2 18 ‐2.30 [‐5.56, 0.96]
Sakzewski 2015a Baseline to 2 weeks to 4 months post‐intervention (change) ‐1.0 5.0 24 1.0 6.0 19 ‐2.00 [‐5.36, 1.36]
Sakzewski 2015a                
Pediatric Evaluation of Disability Inventory (PEDI): Self‐care ‐ Functional Skills domain
Hoare 2013 Baseline to immediately following intervention (change) 9.56 7.95 17 8.04 5.59 17 1.52 [‐3.10, 6.14]
Hoare 2013 Baseline to 2 weeks to 4 months post‐intervention (change) 10.35 7.0 17 12.19 8.28 17 ‐1.84 [‐6.99, 3.31]
Hoare 2013                
PEDI: Self‐care ‐ Caregiver Assistance domain
Hoare 2013 Baseline to immediately following intervention (change) 9.43 10.8 17 9.09 9.27 17 0.34 [‐6.43, 7.11]
Hoare 2013 Baseline to 2 weeks to 4 months post‐intervention (change) 9.91 16.19 17 12.59 12.95 17 ‐2.68 [‐12.54, 7.18]
Hoare 2013                
Functional Independence Measure for Children (WeeFIM)
Chen 2014 Baseline to immediately following intervention (change) 3.04 0.98 23 2.32 0.48 22 0.72 [0.27, 1.17]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 5.22 1.44 23 4.36 0.73 22 0.86 [0.20, 1.52]
Chen 2014 Baseline to 5 to 6 months post‐intervention (change) 7.26 2.03 23 6.0 1.11 22 1.26 [0.31, 2.21]
Modified Ashworth Scale (MAS) ‐ Elbow flexors
Wallen 2011 Baseline to immediately following intervention (change) ‐0.16 0.85 25 ‐0.06 0.91 25 ‐0.10 [‐0.59, 0.39]
Wallen 2011 Baseline to 2 weeks to 4 months post‐intervention (change) ‐0.18 0.93 25 ‐0.08 0.83 25 ‐0.10 [‐0.59, 0.39]
Wallen 2011                
MAS ‐ Wrist flexors
Wallen 2011 Baseline to immediately following intervention (change) ‐0.2 0.62 25 ‐0.04 0.75 25 ‐0.16 [‐0.54, 0.22]
Wallen 2011 Baseline to 2 weeks to 4 months post‐intervention (change) 0.0 0.74 25 0.04 0.69 25 ‐0.04 [‐0.44, 0.36]
Wallen 2011                
Modified Tardieu Scale (MTS) ‐ Elbow flexors
Hoare 2013 Baseline to immediately following intervention (change)
(R2 ‐ R1)		 ‐15.9 35.16 17 ‐21.77 36.87 17 5.87 [‐18.35, 30.09]
Hoare 2013 Baseline to 2 weeks to 4 months post‐intervention (change)
(R2 ‐ R1)		 ‐10.29 46.15 17 ‐3.53 48.31 17 ‐6.76 [‐38.52, 25.00]
Hoare 2013                
Wallen 2011 Baseline to immediately following intervention (change) (R1 only) 4.6 31.0 25 ‐1.36 41.91 25 3.28 [‐19.68, 26.24]
Wallen 2011 Baseline to 2 weeks to 4 months post‐intervention (change) (R1 only) ‐0.52 37.15 25 1.32 49.71 25 ‐1.84 [‐26.17, 22.49]
Wallen 2011                
MTS ‐ Wrist flexors
Hoare 2013 Baseline to immediately following intervention (change)
(R2 ‐ R1)		 ‐2.94 9.85 17 ‐12.65 23.92 17 9.71 [‐2.59, 22.01]
Hoare 2013 Baseline to 2 weeks to 4 months post‐post‐intervention (change)
(R2 ‐ R1)		 ‐4.12 11.76 17 ‐12.65 22.58 17 8.53 [‐3.57, 20.63]
Hoare 2013                
Wallen 2011 Baseline to immediately following intervention (change) (R1 only) 10.36 23.64 25 0.32 29.31 25 10.04 [‐4.72, 24.80]
Wallen 2011 Baseline to 2 weeks to 4 months post‐intervention (change) (R1 only) 3.08 32.32 25 ‐6.96 30.30 25 10.04 [‐7.33, 27.41]
Wallen 2011                
Cerebral Palsy Quality of Life (CP QOL) (Proxy) ‐ Social Wellbeing and Acceptance
Chen 2014 Baseline to immediately following intervention (change) 9.4 1.9 11 6.3 5.4 11 3.10 [‐0.28, 6.48]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 14.5 3.1 11 10.1 5.2 11 4.40 [0.82, 7.98]
Chen 2014                
CP QOL (Proxy) ‐ Function
Chen 2014 Baseline to immediately following intervention (change) 10.0 3.9 11 8.6 5.5 11 1.40 [‐2.58, 5.38]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 13.8 6.4 11 11.6 5.8 11 2.20 [‐2.90, 7.30]
Chen 2014                
CP QOL (Proxy) ‐ Participation and Physical Health
Chen 2014 Baseline to immediately following intervention (change) 8.3 5.4 11 8.7 4.9 11 ‐0.40 [‐4.71, 3.91]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 11.7 8.0 11 12.1 5.3 11 ‐0.40 [‐6.07, 5.27]
Chen 2014                
CP QOL (Proxy) ‐ Emotional Wellbeing and Self‐esteem
Chen 2014 Baseline to immediately following intervention (change) 10.2 3.8 11 8.5 5.5 11 1.70 [‐2.25, 5.65]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 14.8 4.5 11 12.5 5.0 11 2.30 [‐1.68, 6.28]
Chen 2014                
CP QOL (Proxy) ‐ Pain and Impact of Disability (lower score = better)
Chen 2014 Baseline to immediately following intervention (change) 11.9 3.1 11 10.2 6.4 11 1.70 [‐2.50, 5.90]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 18.6 10.1 11 14.3 6.0 11 4.30 [‐2.64, 11.24]
Chen 2014                
CP QOL (Proxy) ‐ Access
Chen 2014 Baseline to immediately following intervention (change) 9.5 2.9 11 8.9 5.3 11 0.60 [‐2.97, 4.17]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 14.5 6.4 11 11.6 7.0 11 2.90 [‐2.71, 8.51]
Chen 2014                
CP QOL (Proxy) ‐ Family Health
Chen 2014 Baseline to immediately following intervention (change) 10.8 4.5 11 9.9 5.0 11 0.90 [‐3.08, 4.88]
Chen 2014 Baseline to 2 weeks to 4 months post‐intervention (change) 14.5 2.1 11 12.8 1.7 11 1.70 [0.10, 3.30]
Chen 2014