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. 2019 Mar 11;116(13):6308–6312. doi: 10.1073/pnas.1819799116

Table 1.

Characteristics of HCCscreen features and their coefficients

Feature class Features Coefficients
cfDNA TP53 other than R249S 2.02
TP53 R249S 0.21
TERT 1.37
SV_TERT 0.70
CTNNB1 1.20
AXIN1 0.01
HBV integrations 0.82
cfDNA concentration −0.27
Protein AFP 0.21
DCP 1.59
Clinical information gender 0.66
age 1.69
(Intercept) −2.68

Penalized logistic regression: λ = 0.14; α = 0.