Representative tracings of mean arterial pressure (MAP), cardiac output (CO), and systemic vascular resistance (SVR) from a Voluntary HV, POTS-HV, and Panic subject. MAP increased in POTS-HV and Panic, decreased in Voluntary HV with the onset of upright hyperventilation. CO decreased in POTS-HV but increased in Panic and Voluntary HV. SVR increased similarly in POTS-HV and Panic but decreased markedly in Voluntary HV. HV, hyperventilation; Panic, panic disorder.