Table 1. Gene ontology analysis of differentially expressed genes associated with response of esophageal squamous cell carcinomas to neoadjuvant chemoradiotherapy.
Results of the top five biological process, cellular component and molecular function.
| Category | GO ID | Term | Count | % | P |
|---|---|---|---|---|---|
| BP | GO:0044236 | multicellular organism metabolic process | 6 | 5.71 | 0.000198 |
| BP | GO:0010770 | positive regulation of cell morphogenesis involved in differentiation | 5 | 4.76 | 0.001407 |
| BP | GO:0030178 | negative regulation of Wnt signaling pathway | 4 | 3.81 | 0.034422 |
| BP | GO:0010720 | positive regulation of cell development | 8 | 7.62 | 0.007031 |
| BP | GO:0042307 | positive regulation of protein import | 3 | 2.86 | 0.02106 |
| CC | GO:0005578 | proteinaceous extracellular matrix | 9 | 8.04 | 0.000389 |
| CC | GO:0001533 | cornified envelope | 4 | 3.57 | 0.000622 |
| CC | GO:0016323 | basolateral plasma membrane | 5 | 4.46 | 0.008398 |
| CC | GO:0030424 | axon | 7 | 6.25 | 0.009971 |
| CC | GO:0055037 | recycling endosome | 4 | 3.57 | 0.015016 |
| MF | GO:0005539 | glycosaminoglycan binding | 7 | 6.80 | 0.000223 |
| MF | GO:0008191 | metalloendopeptidase inhibitor activity | 2 | 1.94 | 0.003633 |
| MF | GO:0033612 | receptor serine | 2 | 1.94 | 0.003633 |
| MF | GO:0008083 | growth factor activity | 4 | 3.88 | 0.017013 |
| MF | GO:0031406 | carboxylic acid binding | 4 | 3.88 | 0.019548 |
Notes.
Abbreviation
- BP
- Biological Process
- CC
- Cellular Component
- MF
- Molecular Function