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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: J Med Chem. 2018 Sep 25;61(19):8811–8824. doi: 10.1021/acs.jmedchem.8b00964

Chart 1. A focused library of ten structurally related Mn-PyC3A-derived complexes were evaluated as liver-specific MRI contrast agents.

Chart 1.

(A) Structures of Mn-PyC3A and Mn-PyC3A-derived complexes, (B) derivatives of varying lipophilicity were prepared via modifications to the 2-methylpyridine arm of the Mn chelates.