Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 20;3(4):542–557. doi: 10.1002/hep4.1322

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Primary and secondary BAs. Each Color represents a study group. Box plots demonstrating relative levels of (A) primary BAs and (B) secondary BAs among the study cohorts. (C‐E) qRT‐PCR of hepatic mRNA expression of genes related to (C) BA biosynthesis, (D) BA export and uptake, and (E) nuclear receptors regulating BA synthesis in controls and patients with AC. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. (F) Serum levels of FGF19, FGF21, and GLP‐1 in controls, HDs, and those with ALD. Abbreviations: CA, cholate; GCA, glycocholate; SHP, small heterodimer partner; TβMCA, tauro‐beta‐muricholate.