. Author manuscript; available in PMC: 2019 Jul 15.

Published in final edited form as: Bioorg Med Chem Lett. 2018 May 23;28(13):2302–2313. doi: 10.1016/j.bmcl.2018.05.024

Table 2.

IC₅₀ values and some physico-chemical properties for adamantyl-aryl sEH inhibitors 2a-c

Solubilities were measured in sodium phosphate buffer (pH 7.4, 0.1 M) containing 1% of DMSO.

As determined via a kinetic fluorescent assay. Results are means of three separate experiments.30