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. Author manuscript; available in PMC: 2019 Jul 15.
Published in final edited form as: Bioorg Med Chem Lett. 2018 May 23;28(13):2302–2313. doi: 10.1016/j.bmcl.2018.05.024

Table 3.

IC50 values and some physico-chemical properties for adamantyl-aryl sEH inhibitors 3a-j, 4a-f and 5

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a

Solubilities were measured in sodium phosphate buffer (pH 7.4, 0.1 M) containing 1% of DMSO.

b

As determined via a kinetic fluorescent assay. Results are means of three separate experiments.29

c

DAU: 1,3-diadamantyl urea