Table 6.

Relative effect of different factors on eNOS superoxide and NO production

Superoxide Production	Pterin	Substrate	Other	NOSynthesis
+++	None	l-arginine		None
+++	None	ADMA		None
+++	None	None		None
++	BH2	l-arginine		None
++	BH2	None		None
+	BH4	l-arginine	S1177p	+
=	BH4	l-arginine		=
=	BH4	l-arginine	T495p	–

Qualitative assessment based on data from Refs. 150, 161, 250, 334, 753, 973, 974, 1033. ADMA, asymmetric dimethylarginine; eNOS, endothelial nitric oxide synthase; NO, nitric oxide.