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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Bioorg Med Chem. 2018 Nov 20;27(1):125–132. doi: 10.1016/j.bmc.2018.11.027

Figure 1.

Figure 1.

Heroin immunoconjugate vaccine strategy. A) Heroin hapten activation, conjugation, and vaccination strategy; B) Structures of relevant vaccine immunoconjugates and adjuvants. Heroin hapten was synthesized according to literature methods.1-2