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. Author manuscript; available in PMC: 2020 Mar 29.

Published in final edited form as: Circ Res. 2019 Mar 29;124(7):1071–1093. doi: 10.1161/CIRCRESAHA.118.313221

A. Renal denervation using catheter-based approach. Some renal nerves near the ostium, the inferior suprarenal artery, and accessory arteries (not shown) do not run along the adventitia of the main renal artery and therefore are not susceptible to catheter-based ablation. The radiofrequency catheter is shown in gray. B. Renal tissue NE concentrations in obese dogs after catheter-based RDN (From Henegar et al. Am J Hypertens. 2014;27:1285–1292) or surgical RDN (From Lohmeier et al. Hypertension. 2012;59:331–338).

A. Renal denervation using catheter-based approach. Some renal nerves near the ostium, the inferior suprarenal artery, and accessory arteries (not shown) do not run along the adventitia of the main renal artery and therefore are not susceptible to catheter-based ablation. The radiofrequency catheter is shown in gray. B. Renal tissue NE concentrations in obese dogs after catheter-based RDN (From Henegar et al. Am J Hypertens. 2014;27:1285–1292) or surgical RDN (From Lohmeier et al. Hypertension. 2012;59:331–338).