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. 2019 Mar 5;10(19):1812–1828. doi: 10.18632/oncotarget.26737

Figure 7. Vaccine-activated CD4+ T cells maintain Th1 cytokine production and secrete IL-2 at priming.

Figure 7

Purified CD4+ T cells were primed and repetitively boosted (8x) with Mel202/DR1/CD80 vaccine cells. (A) IFNγ, (B) TNFα and (C) IL-2-release in the supernatant was measured by a flowcytometric multiplex bead array after prime and boosts 1-8. Purity of CD4+ T cells was >90% throughout the course of the experiments. Data are representative of two independent experiments with purified CD4+ T cells for each donor 1, 2, and 3.