Table 2. miRNA differential expression analysis.
| FAs vs DICER1-mutant FAs | FVPTCs vs DICER1-mutant FAs | FAs vs FVPTCs | ||||
|---|---|---|---|---|---|---|
| miRNA | log FC | FDR | log FC | FDR | log FC | FDR |
| hsa-miR-106a-5p + hsa-miR-17-5p | -3.32 | 0.0009 | ||||
| hsa-miR-106b-5p | -4.47 | 0.0079 | -2.07 | 0.0281 | ||
| hsa-miR-126-3p | 2.57 | 0.0100 | -0.81 | 0.0343 | ||
| hsa-miR-135a-5p | -2.65 | 0.0076 | ||||
| hsa-miR-135b-5p | -5.61 | 0.0002 | -4.86 | 0.0007 | ||
| hsa-miR-146b-5p | 3.29 | 0.0322 | ||||
| hsa-miR-148b-3p | 2.92 | 0.0144 | 3.65 | 0.0029 | ||
| hsa-miR-151a-5p | -4.89 | 0.0041 | ||||
| hsa-miR-152-3p | 7.62 | <0.0001 | -2.61 | 0.0130 | ||
| hsa-miR-15b-5p | -3.45 | 0.0076 | -2.70 | 0.0273 | ||
| hsa-miR-181a-3p | 5.57 | 0.0012 | 5.36 | 0.0010 | ||
| hsa-miR-181a-5p | -1.96 | 0.0487 | ||||
| hsa-miR-185-5p | -2.10 | 0.0199 | ||||
| hsa-miR-191-5p | -2.92 | 0.0009 | -2.56 | 0.0025 | ||
| hsa-miR-195-5p | -2.70 | 0.0281 | ||||
| hsa-miR-19a-3p | 6.80 | 0.0034 | -2.12 | 0.0482 | ||
| hsa-miR-19b-3p | 3.75 | 0.0100 | -1.06 | 0.0495 | ||
| hsa-miR-200c-3p | 2.69 | 0.0218 | ||||
| hsa-miR-204-5p | -2.87 | 0.0465 | ||||
| hsa-miR-221-3p | 3.80 | 0.0343 | ||||
| hsa-miR-222-3p | 2.46 | 0.0192 | ||||
| hsa-miR-20a-5p + hsa-miR-20b-5p | -3.08 | 0.0222 | -3.29 | 0.0030 | ||
| hsa-miR-25-3p | 2.12 | 0.0487 | ||||
| hsa-miR-28-5p | -2.61 | 0.0123 | -1.72 | 0.0394 | ||
| hsa-miR-296-5p | -2.40 | 0.0130 | ||||
| hsa-miR-301a-3p | 4.18 | 0.0136 | 5.55 | 0.0273 | ||
| hsa-miR-30c-5p | -6.18 | 0.0003 | -5.22 | 0.0004 | ||
| hsa-miR-30d-5p | -2.92 | 0.0123 | -2.78 | 0.0025 | ||
| hsa-miR-30e-3p | 5.61 | 0.0281 | -2.97 | 0.0130 | ||
| hsa-miR-30e-5p | -3.90 | 0.0037 | -3.00 | 0.0042 | -0.90 | 0.0495 |
| hsa-miR-3151-5p | -3.63 | 0.0025 | ||||
| hsa-miR-32-5p | -6.61 | 0.0002 | -5.93 | 0.0011 | ||
| hsa-miR-331-3p | -2.30 | 0.0322 | ||||
| hsa-miR-340-5p | -2.25 | 0.0458 | ||||
| hsa-miR-34a-5p | -4.40 | 0.0006 | -4.55 | <0.0001 | ||
| hsa-miR-361-3p | -2.59 | 0.0192 | ||||
| hsa-miR-361-5p | -5.47 | 0.0076 | -5.38 | 0.0001 | ||
| hsa-miR-363-3p | -2.20 | 0.0488 | ||||
| hsa-miR-365a-3p + hsa-miR-365b-3p | -2.51 | 0.0343 | ||||
| hsa-miR-374b-5p | -4.54 | 0.0158 | -1.80 | 0.0495 | ||
| hsa-miR-423-3p | -5.21 | 0.0002 | -2.55 | 0.0130 | ||
| hsa-miR-424-5p | -4.66 | 0.0025 | ||||
| hsa-miR-4286 | 4.02 | 0.0173 | 3.89 | 0.0218 | ||
| hsa-miR-429 | 8.65 | 0.0006 | 8.46 | 0.0010 | ||
| log FC | FDR | log FC | FDR | log FC | FDR | |
| hsa-miR-4454 + hsa-miR-7975 | 1.28 | 0.0343 | ||||
| hsa-miR-4516 | 2.33 | 0.0480 | ||||
| hsa-miR-451a | 2.37 | 0.0218 | ||||
| hsa-miR-454-3p | 5.50 | 0.0174 | -2.36 | 0.0281 | ||
| hsa-miR-518b | -3.24 | 0.0130 | ||||
| hsa-miR-5196-3p + hsa-miR-6732-3p | -2.83 | 0.0192 | ||||
| hsa-miR-660-5p | -2.30 | 0.0385 | ||||
| hsa-miR-98-5p | -2.20 | 0.0135 | -1.88 | 0.0218 | ||
Abbreviations: FAs, follicular adenomas; FVPTCs, follicular variant of papillary thyroid carcinomas; FC, fold change; FDR, false discovery rate.