Table 1. Patient characteristics.

Factors	n (%)
Sex
Female  Male	115 (32.0) 244 (68.0)
Age
<65 years  ≥65 years	223 (62.1) 136 (37.9)
Disease status
Locally advanced Metastatic Recurrence	73 (20.3) 212 (59.1) 74 (20.6)
History of prior chemotherapy
<No  Yes	265 (73.8) 94 (26.2)
ECOG Performance status
0  1, 2	257 (71.6) 102 (28.4)
UGT1A1
Wild Single Double	201 (56.0) 134 (37.3) 15 (4.2)
CA19-9, U/mL median (range)	1071.0 (0.4–368500)
Albumin, g/dL median (range)	3.9 (2.3–5.3)
CRP, mg/dL median (range)	0.3 (0.0–12.4)

Abbreviations: ECOG, Eastern Cooperative Oncology Group; CA19-9, carbohydrate antigen 19-9; CRP, C-reactive protein.