Table 2. Number of proliferating cells in hilus region of the dentate gyrus of neonates.
Age | C57BL/6 | 11β-HSD2−/− |
---|---|---|
P7 | 105±9 (5) | 133±19 (3) |
P14 | 51±7 (4) | 59±7 (5) |
P21 | 19±3 (5) | 11±1 (4)* |
The number of proliferating cells was assessed by BrdU labeling. Cell counts were averaged for each horn of the dentate gyrus of three coronal sections (~Bregma −2.06mm) for each brain. Values are means±S.E.M. (n). *P<0.05 compared to C57BL/6 control.