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. 2019 Mar 6;34(4):659–665. doi: 10.1093/humrep/dez017

Table II.

Effect sizes that studies have 80 and 90% power to detect, and effect sizes that were actually estimated by the studies, including the precision of the estimates as measured by width of 95% CI.

What LBR improvements are studies powered to detect? What LBR improvements are actually estimated in the studies?
80% Power to detect 90% Power to detect Estimated LBR improvement Width of 95% CI
Largest RCT in comparison N = 199 19 (13 to 29)pp 22 (15–33)pp 0 (−4 to 6)pp 25 (16–39)pp
Meta-analysis for comparison N = 199 16 (9 to 27)pp 19 (11–31)pp 0 (−3 to 7)pp 21 (12–34)pp

Data are median (IQR).