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. 2019 Mar 20;15(3):e1006710. doi: 10.1371/journal.pcbi.1006710

Table 2. Scenarios examined through sensitivity analysis.

As each parameter was varied from its default value, all other parameters were held at their default values. Under each parameter scenario, a separate calibration was performed prior to performing vaccination impact projections.

Parameter Low Default High
Human infectiousness Asymptomatic infections have ~80% infectiousness [20] All infections follow the same trajectory of infectiousness [44]
Duration of cross-immunity 180 days 686 days [45]
Distribution of cross-immunity Fixed Exponential
Mosquito infectiousness 0.5 1.0
Mosquito biting rate Multiply default by 0.5 Temperature-dependent [38,39] Multiply default by 2
Mosquito death rate Multiply default by 0.5 Temperature-dependent [35] Multiply default by 2
Extrinsic incubation period Multiply default by 0.5 Temperature-dependent [41] Multiply default by 2
Mosquito movement probability 0.1 0.3 [37] 0.5