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. 2019 Feb 28;52(2):151–156. doi: 10.5483/BMBRep.2019.52.2.213

Fig. 3.

Fig. 3

Mutant KRAS induces overexpression of RAD51. (A) Western blot analysis of RAD51 expression upon KRAS knockdown in KRAS MT cell lines A549 and LU99A, or KRAS WT cell lines NCIH2023 and NCIH3122 cells. Two different siRNAs targeting KRAS were used. (B) Western blot analysis of RAD51 expression upon transient expression of FLAG-tagged WT KRAS or MT KRAS in A549 cells and NCIH3122 cells. (C) Western blot analysis of RAD51 expression upon MYC knockdown in A549 cells. Two different siRNAs targeting MYC were used. (D) Western blot analysis of RAD51 expression upon MYC or control knockdown in combination with overexpression of FLAG-tagged MT KRAS or control in A549 cells.