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. 2019 Mar 6;43(5):2103–2117. doi: 10.3892/ijmm.2019.4126

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Copyright: © Miao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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The effects of FAM20C on salivary parameters. (A) The flow rate of saliva. The volume of saliva obtained from male (^***P<0.001) and female cKO mice (^**P<0.01) was significantly lower than that obtained from control mice. (B) The total protein concentration of the saliva. The total protein concentration was increased in cKO mice ^***P<0.001. The (C) Na⁺, (D) Cl⁻ and (E) K⁺ ion concentrations in the saliva. The Na⁺, Cl⁻ and K⁺ concentrations were significantly increased in saliva from cKO mice compared with saliva from control mice ^**P<0.01. cKO, Fam20c^f/f; Mmtv-Cre conditional knockou; Fam20C, family with sequence similarity 20-member C.